Nagourney Cancer Institute

Pioneer in Cancer Research & Personalized Cancer Treatment

Dr. Robert Nagourney has been a pioneer in cancer research and personalized cancer treatment for over 20 years. He is the founder and medical director of Nagourney Cancer Institute (formerly Rational Therapeutics) and Clinical Professor at the University of California, Irvine School of Medicine.  Also, he is a practicing oncologist and triple board certified in Internal Medicine, Medical Oncology and Hematology.
Dr. Robert Nagourney

Dr. Nagourney Featured on TEDx Talks

Dr. Robert Nagourney has worked 20+ years refining a laboratory technique that measures how cancer cells respond when they are exposed to drugs and drug combinations. Listen as he shares his insight into cancer, cancer research, and his treatment philosophy in this TedX Talk.  Title: The Future of Cancer Research Lies Behind Us.
The Science

The Science

With the functional profiling test, we can help discover the most effective and least toxic drug regimen for you PRIOR to initiating treatment. By using therapies found active in the laboratory, Dr. Nagourney has been able to double response rates and improve survival for his patients. Learn more about the science behind Dr. Nagourney's techniques and outcomes.


Understanding Your Cancer

Choose from the list below to learn more about our work with specific cancer types and those who have been affected by it.
Patient Stories

Patient Stories

Read stories from actual patients and learn about their experience with cancer and their fight to overcome it.


Metastatic Colon Cancer: Doctor Heal Thyself

One year ago, almost to the day, I was asked to see a very pleasant 67-year-old surgeon.  He was personally referred by the radiologist who had just...

The Cost of Cancer Therapy: How Much is Too Much?

There has been much written about the cost of cancer chemotherapy.  In the US alone over 2.5 trillion dollars are spent on healthcare each year. ...

Metastatic Lung Cancer: A Patient with 9 Lives

In September of 2013, I was asked to see a patient with metastatic adenocarcinoma of the lung.

Treatment with Chemotherapy  

Biopsies did not reveal...