Dr. Nagourney's Blog

Recurrent BRCA Positive Ovarian Cancer: An Unexpected Opportunity

For the over 22,000 women in the United States diagnosed each year with ovarian cancer outcomes have improved slowly, yet the majority of these women still do not survive five years. Despite these statistics, ovarian cancer remains one of the...

Stage 4 Uterine Cancer & BRCA Gene Mutation Story Gets Interesting

  The discovery of the BRCA genes by Mary Claire King and Mark Skolnick in the 1990s provided immense insights. It explained...

BRCA Prostate Cancer: Lessons Learned from a Successful Outcome

On March 29, 2016, we reported the story of a 55 year old man diagnosed 13 years earlier with prostate cancer who had failed...

Aggressive Prostate Cancer: A Life-Saving Opportunity Nearly Missed

A 42 year old gentleman presented in 2003 with an aggressive prostate cancer. He underwent surgery, radiation, hormones,...

Triple Negative Breast Cancer - Worse or Just Different?

The term “triple negative breast cancer” (TNBC) is applied to a subtype of breast cancers that do not express the estrogen or...

The Angelina Jolie Effect

Angelina Jolie’s willingness to bravely publish her saga, as she confronts the risk of a nefarious form of cancer, has focused...

Can PARP Inhibitors be Tested Using the EVA-PCD Assay?

Poly ADP ribose polymerase (PARP) is a nuclear enzyme associated with response to DNA damage. Following single strand DNA...